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fmr1 gene card

Angiotensin-converting Enzyme 2 (ACE2)-CHO Cell Line Model for COVID-19: Helps researchers to further study the interaction between the receptor ACE2 and the COVID-19 virus. These reagents reveal the extent of methylation of each individual allele in both male and female samples, and thus eliminate the need to … Binds to 5'-ACU[GU]-3' and/or 5'-[AU]GGA-3' RNA consensus sequences within mRNA targets, mainly at coding sequence (CDS) and 3'-untranslated region (UTR) and less frequently at 5'-UTR (PubMed:23235829). Phosphorylation has no effect on the binding of individual mRNA species, but may affect the association with polyribosome. h�b```�b�Pa��1�'��u^=@�����ҭ�B��c`*��`J��h(�h�)vN�P -�B`��@��QG����/�v0l`0ڰ���$�mY��}ğ�F���`�d�Ҍ������YQ�� �#�

B׎�.�o�k_ ��_��7��C!#�mw$����c�:�4�;�H��p��%a�Iw����h�r�FH�SH�Rr��R_ˍ/�߻�0��O��7�ͪ�|z7���=��w�!������y�?���MY������8�. Transcription Factor Targets and Binds to a large subset of dendritic mRNAs that encode a myriad of proteins involved in pre- and postsynaptic functions (PubMed:7692601, PubMed:11719189, PubMed:11157796, PubMed:12594214, PubMed:17417632, PubMed:23235829, PubMed:24448548). Arg-445 is dimethylated, probably to asymmetric dimethylarginine.

The number of samples tested on this page include samples from the targeted GeneCards Summary for FMR1 Gene: FMR1 (fragile X mental retardation 1) is a protein-coding gene.

The KH domains are necessary for mediating miRNA annealing to specific RNA targets (PubMed:17057366). The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2. You can see

Len. Genome Browser and Ensembl. View protein in InterPro IPR008395, Agenet-like_dom IPR040148, FMR1 IPR040472, FMRP_KH0 IPR004087, KH_dom IPR004088, KH_dom_type_1 IPR036612, KH_dom_type_1_sf IPR041560 The PANTHER Classification System To accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.

To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.

lentivirus, AAV, adenovirus, MMLV, MSCV, baculovirus), VectorBuilder Custom and pre-made pooled libraries (ie. 7 RefSeqs (NM) Availability. mutation, so the total number of samples determined by simply summing the After adjusting a filter, press Apply The table currently shows only high value (numeric) copy number data. Chr.X: 147937310-147937828 on GRCh38; Amp. For TCGA samples, Ascat algorithm is used to calculate the average ploidy. Home EXPLORE MORE; About Us .

An important paralog of this gene is FXR1. For CGP samples, Picnic algorithm is used to calculate the average ploidy. An important paralog of this gene is FXR1. All services and products are only for lab research use, not for any clinical diagnosis or treatment. gene expression, shRNA knockdown, CRISPR), VectorBuilder Viral vectors for FMR1 (ie. Fragile X mental retardation 1 protein (FMR1_HUMAN), * FMR1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector -, * Gene synthesis, site-directed mutagenesis, subcloning, and more services -, * FMR1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector -, A. gosspyii yeast (Eremothecium gossypii), Actinobacteria (Mycobacterium tuberculosis), African malaria mosquito (Anopheles gambiae), Alpha proteobacteria (Wolbachia pipientis), Beta proteobacteria (Neisseria meningitidis), Firmicute Bacteria (Streptococcus pneumoniae), Fission Yeast (Schizosaccharomyces pombe), Schistosome Parasite (Schistosoma mansoni), Sea Urchin (Strongylocentrotus purpuratus). Isoform 6 interacts with CYFIP2; this interaction occurs in a RNA-dependent manner (PubMed:24658146). CIViC Summary , ... ≥1 Filter Card (with 10 complete blood spots) See Sample Requirements Page for detailed information.

Forms heterodimer with FXR1; heterodimerization occurs in a methylation-dependent manner (PubMed:7489725, PubMed:11157796, PubMed:16636078). shows the number of samples recorded as having a particular type of ; Evidence={ECO:0000305}; Sequence=AAA62466.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAA62467.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; The mechanism of the severe phenotype in the Asn-304 patient lies in the sequestration of bound mRNAs in nontranslatable mRNP particles. Copyright © 1996-2020 , Weizmann Institute of Science. Interacts with RANBP9 (via C-terminus); this interaction is direct and inhibits binding of FMR1 to RNA homopolymer (PubMed:15381419). For more detailed information about copy number data and gain/loss definitions click here.

Part of a ribonucleoprotein complex with AGO2/EIF2C2 and miRNAs (PubMed:14703574). This gene was present in the common ancestor of animals. Restrict the view to a region of

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